GIT2 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： GIT2 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： GIT2 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00009815-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human GIT2 protein.
- Immunogen:
- GIT2 (NP_631940.1, 1 a.a. ~ 471 a.a) full-length human protein.
- Sequence:
- MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQSLSNHLFEELAMDMYDEVDRRETDAVWLATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Flow Cytometry
enlarge this image- FACS analysis of negative control 293 cells (Black) and GIT2 expressing 293 cells (Green) using GIT2 purified MaxPab mouse polyclonal antibody.
- Western Blot (Tissue lysate)
- GIT2 MaxPab polyclonal antibody. Western Blot analysis of GIT2 expression in human pancreas.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of GIT2 expression in transfected 293T cell line (H00009815-T01) by GIT2 MaxPab polyclonal antibody.
Lane 1: GIT2 transfected lysate(51.81 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 9815
- GeneBank Accession#:
- NM_139201
- Protein Accession#:
- NP_631940.1
- Gene Name:
- GIT2
- Gene Alias:
- CAT-2,DKFZp686G01261,KIAA0148,MGC760
- Gene Description:
- G protein-coupled receptor kinase interacting ArfGAP 2
- Omim ID:
- 608564
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq
- Other Designations:
- ARF GTPase-activating protein GIT2,G protein-coupled receptor kinase interactor 2,GRK-interacting protein 2,cool-associated, tyrosine phosphorylated protein 2
- Gene Pathway